Copyright © 2009 by "International Journal of Pharmaceutica Research and Development" · All Rights reserved · E-Mail: info@ijprd.com
HOW TO PREPARE
YOUR PAPER
YOUR PAPER
Past Issues
March 2009
April 2009
May 2009
June 2009
July 2009
August 2009
September 2009
October 2009
November 2009
December 2009
March 2009
April 2009
May 2009
June 2009
July 2009
August 2009
September 2009
October 2009
November 2009
December 2009
Online Since : March 2009
Only 10 Articles will be Published in Each Issues
TODAY IS
INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH AND DEVELOPMENT
Article No 7
October -2009 / Volume - 1 /Issue - 8/ Article No - 7 / Review Article
VARIOUS EMERGING TECHNOLOGIES IN INSULIN DELIVERY SYSTEM
Pandey Shivanand*1, Patel Jigisha,
Patel Kinjal1
October -2009 / Volume - 1 /Issue - 8/ Article No - 7 / Review Article
VARIOUS EMERGING TECHNOLOGIES IN INSULIN DELIVERY SYSTEM
Pandey Shivanand*1, Patel Jigisha,
Patel Kinjal1
ABSTRACT:
In today's era, insulin delivery by alternative route is a area of current interest in the design of drug delivery system. Most of the global pharmaceutical companies are showing encouraging progress in their attempts to develop alternative insulin delivery technologies. For most patients with type 1 diabetes, the tedious part of the treatment is to tolerate needle after needle, both for glucose measurement and to deliver insulin. The introduction of insulin therapy years ago has saved the lives of millions of patients with diabetes. The development of technologies in the last decade have brought to limelight the strategies that hold some promise in turning non-injectable insulin delivery from theory to reality. A rigorous research effort has been undertaken worldwide to replace the authentic subcutaneous route by a more accurate and non-invasive route. Considerable progress has been made to achieve new milestones for effective treatment of diabetes. Peroral, nasal, and pulmonary administration has demonstrated good potential for treatment of diabetes. In addition, transmucosal, buccal, ocular, rectal, and vaginal routes of insulin have also shown to decrease serum glucose concentrations. The transdermal route using various technologies also exhibits success in delivering insulin.
Keywords: type 1 diabetes, insulin therapy, non-injectable, vaginal routes of insulin, , transmucosal
In today's era, insulin delivery by alternative route is a area of current interest in the design of drug delivery system. Most of the global pharmaceutical companies are showing encouraging progress in their attempts to develop alternative insulin delivery technologies. For most patients with type 1 diabetes, the tedious part of the treatment is to tolerate needle after needle, both for glucose measurement and to deliver insulin. The introduction of insulin therapy years ago has saved the lives of millions of patients with diabetes. The development of technologies in the last decade have brought to limelight the strategies that hold some promise in turning non-injectable insulin delivery from theory to reality. A rigorous research effort has been undertaken worldwide to replace the authentic subcutaneous route by a more accurate and non-invasive route. Considerable progress has been made to achieve new milestones for effective treatment of diabetes. Peroral, nasal, and pulmonary administration has demonstrated good potential for treatment of diabetes. In addition, transmucosal, buccal, ocular, rectal, and vaginal routes of insulin have also shown to decrease serum glucose concentrations. The transdermal route using various technologies also exhibits success in delivering insulin.
Keywords: type 1 diabetes, insulin therapy, non-injectable, vaginal routes of insulin, , transmucosal
IJPRD
Mr.Pandey Shivanand
1: Smt. R. B. P. M. Pharmacy College, Atkot-360040, Rajkot, Gujarat. India
