Copyright © 2009 by "International Journal of Pharmaceutica Research and Development" · All Rights reserved · E-Mail: info@ijprd.com
HOW TO PREPARE
YOUR PAPER
YOUR PAPER
Past Issues
March 2009
April 2009
May 2009
June 2009
July 2009
August 2009
September 2009
October 2009
November 2009
December 2009
March 2009
April 2009
May 2009
June 2009
July 2009
August 2009
September 2009
October 2009
November 2009
December 2009
Online Since : March 2009
Only 10 Articles will be Published in Each Issues
TODAY IS
INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH AND DEVELOPMENT
Article No 07
September -2009 / Volume - 1 / Issue - 7/ Article No - 8 / Research Article
ANTHELMINTIC EFFECT OF TAMARIND INDICA LINN LEAVES JUICE EXRACT ON PHERETIMA POSTHUMA
VAISHALI M. SAMPAT1,VAISHALI M. MUTE1,
KETA A. PATEL1, KUSHAL SANGHAVI1 ,
DIPIN MIRCHANDANI1, PARTH C. BABARIA1
September -2009 / Volume - 1 / Issue - 7/ Article No - 8 / Research Article
ANTHELMINTIC EFFECT OF TAMARIND INDICA LINN LEAVES JUICE EXRACT ON PHERETIMA POSTHUMA
VAISHALI M. SAMPAT1,VAISHALI M. MUTE1,
KETA A. PATEL1, KUSHAL SANGHAVI1 ,
DIPIN MIRCHANDANI1, PARTH C. BABARIA1
Miss. Sampat Vaishali
1MAEER’s Maharashtra Institute of Pharmacy, MIT Campus, Pune -411 038, Maharashtra, India.
ABSTRACT -
The aim of present study is to evaluate Anthelmintic potential of juice of Tamarind Indica Linn leaves using Pheretima posthuma as test worms. Various concentrations (100%, 50%, 20%) of Tamarind indica linn leaves juice were tested in the assay, which involved determination of time of paralysis (P) and time of death (D) of the worms.
It show shortest time of paralysis (P=23.5 min) and death (D=62min) in 100% concentration, while the time of paralysis and death will increase in 50% concentration (P=26min&D=65min) and in 20% concentration (P=30min&D=72min) respectively as compare to Piperazine citrate (10mg/ml) used as standard reference (P= 23 min& D= 60 ) and distilled water as control. The results of present study indicated that the juice of Tamarindus indica linn leaves showed significantly demonstrated paralysis, and also caused death of worms especially at higher concentration as compared to standard reference Piperazine citrate and control.
From the result it is conclude that the juice of Tamarindus Indica linn leaves showed significant Anthelmintic activity.
KEY WORDS: Pheretima posthuma , Anthelmintic, Tamarindus Indica linn leaves,
Piperazine citrate.
The aim of present study is to evaluate Anthelmintic potential of juice of Tamarind Indica Linn leaves using Pheretima posthuma as test worms. Various concentrations (100%, 50%, 20%) of Tamarind indica linn leaves juice were tested in the assay, which involved determination of time of paralysis (P) and time of death (D) of the worms.
It show shortest time of paralysis (P=23.5 min) and death (D=62min) in 100% concentration, while the time of paralysis and death will increase in 50% concentration (P=26min&D=65min) and in 20% concentration (P=30min&D=72min) respectively as compare to Piperazine citrate (10mg/ml) used as standard reference (P= 23 min& D= 60 ) and distilled water as control. The results of present study indicated that the juice of Tamarindus indica linn leaves showed significantly demonstrated paralysis, and also caused death of worms especially at higher concentration as compared to standard reference Piperazine citrate and control.
From the result it is conclude that the juice of Tamarindus Indica linn leaves showed significant Anthelmintic activity.
KEY WORDS: Pheretima posthuma , Anthelmintic, Tamarindus Indica linn leaves,
Piperazine citrate.
