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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH AND DEVELOPMENT
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ABSTRACT

  The purpose  of  this  research  was  to  study  the  non-aqueous  film  coating  of  tablets  utilizing  a  laboratory   scale  perforated   coating  pan  apparatus. The  important   process  parameter  of  with  respect  to  film  quality  were  evaluated  by  using  trial  batches. Tablet  were  evaluated  for  coating  uniformity(mg),  coating  process  efficiency (%)  &  surface  roughness.  The Spray rate, atomization  air  pressure, distance  of   nozzle  from  tablet  bed, inlet  air  temperature,  pan  differential  pressure, pan  speed and  %  solid  content  these affect  on  final  film  quality  of  coated  tablets. The  process  parameters   related  to  perforated  pan  coating  process  can  be  identified  and  optimized. 




        

Key words:
Non-aqueous  film  coating,  coating  uniformity,  coating    process  efficiency, perforated   coating  pan. 
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Article No 4
September - 2010 / Volume - 2 / Issue - 7  / Article No - 4 / Review Article

STUDIES IN OPTIMIZATION OF NON AQUEOUS FILM COATING PARAMETERS


Rohokale BS1*,
Jadhav VM2, Kadam VJ3



1Bharati Vidyapeeth College of Pharmacy,
CBD Belapur, Navi Mumbai-4000614.(MS)
2Formulation and Development Department ,
Holden Medical Laboratories Pvt Ltd, Nashik (MS).
Email : rajrohokale@yahoo.com
Rohakale B.S.
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