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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH AND DEVELOPMENT
Article No 2
August -2009 / Volume - 6 / Article No - 1 / Research Article
ANTHELMINTIC POTENTIAL OF DENDROPHTHOE FALCATA ETTING.(L.F.) LEAF
Mr.Dipak Raut
1 A.V.C.O.P., Sangamner, Dist-Ahmednagar, M.S.-422608
2 N. D. M. V. P. S’s College of Pharmacy, Nashik, (MS), India-422002
3 Division of Pharmacognosy, Department of Pharmaceutical technology, Jadavpur University, Kolkata, India-700032
*E-mail: dipak_raut2000@rediffmail.com
Dipak N. Raut1*, Subodh C. Pal2, Subhash C. Mandal3
ABSTRACT
Dendrophthoe falcata (L.f.) Etting. Belonging to family Loranthaceae is an evergreen parasitic plant grown on different host plant throughout India. Present study is carried out to investigate and prove ethnomedicinal value of the plant. Authenticated plant leaves were taken for the study includes extraction of leaves using different solvents and evaluation of anthelmintic activities. Coarse dried leaves of the plant were extracted successively by soxhlet using petroleum ether, chloroform, ethyl acetate and methanol as solvents according to their increasing polarity. Dried extracts were tested for anthelmintic activity using Pherotima postuma as a species of earth worm and compare the paralysis time and death time with standard drug albendazole. Ethyl acetate and methanol extracts shows comparable anthelmintic activity with standard drug albendazole. Methanol and ethyl acetate extracts were tested by different chemical tests. It shows presence of tannins, flavonoids, terpenoids. These phytoconstituents may be responsible for the said activities.
Key words : Parasitic plant, Dendrophthoe falcata, anthelmintic, phytoconstituents.